Overview

SCIENTIFIC SCORE
Possibly Effective
Based on 29 Researches
7.1
USERS' SCORE
Good
Based on 6 Reviews
8.1
Supplement Facts
Serving Size:  1 Softgel
Amount Per Serving
%DV
Calories
15
 
Total Fat
1.5 g
2%**
Saturated Fat 
0.5 g
3%**
Cholesterol
10 mg
3%
Fish Oilprovides 360 mg of Total Omega-3 Fatty Acids†comprising of:EPA (Eicosapentaenoic Acid)DHA (Docosahexaenoic Acid)Other Fatty Acids
1,200 mg (1.2 g)
***************

Top Medical Research Studies

We examined the relationship between plasma omega-3 levels and heart failure (HF), focusing on how this affects mortality in patients with existing HF. Our analysis of the UK Biobank, which included nearly 272,000 participants without HF, showed that higher omega-3 levels were linked to a 21% lower risk of developing HF over nearly 14 years.

For those already diagnosed with HF, higher omega-3 levels significantly reduced the risk of all-cause and cardiovascular mortality by around 50%. These findings suggest that boosting omega-3 intake could be beneficial for heart health.
Read More
We investigated how eicosapentaenoic acid (EPA) affects heart rhythm, particularly in the context of high-fat diets. In our study, mice were divided into two groups: one received a high-fat diet, while the other’s diet was supplemented with EPA for eight weeks.

We observed that the mice on a high-fat diet experienced severe heart rhythm issues, such as bradycardia and atrial fibrillation (AF). In contrast, the EPA group showed significantly less AF and better heart function. These results suggest that including EPA in the diet could be a promising strategy to support heart health and reduce the risk of arrhythmias.
Read More
9
High-dose omega-3 improves heart function
We explored how omega-3 polyunsaturated fatty acids (PUFAs) can help manage heart failure by analyzing 14 randomized controlled trials involving over 9,000 participants.

Our findings revealed that high doses—between 2000 and 4000 mg daily—taken for at least a year, remarkably improved heart function.

However, lower doses or shorter treatment periods didn’t show the same benefits. Notably, there were no increased risks of adverse events or dropout rates in those taking omega-3 compared to control groups.
Read More

Most Useful Reviews

9
Mood and heart benefits
1 people found this helpful
Fish Oil is remarkable! I believe it's assisting with my mood swings. Initially bought for my daughter, we now share it. I've noticed I'm less irritable, and it appears beneficial for heart disease and my autoimmune issues. The softgels are easy to swallow. I recommend purchasing, and I’ll continue using it!
Read More
7.5
Supports heart health
427 people found this helpful
Wonderful! This fish oil is excellent as Omega 3 can reduce the risk of heart disease and improve blood circulation. It enhances cognitive functions and helps lower blood pressure. My family consistently takes omega, and the price-quality ratio is ideal. The capsules are quite large but easy to swallow.
Read More
8
Nervous system benefits
1 people found this helpful
The quality is superb with a halal composition. It's beneficial for heart disease, immunity, and brain development. It’s recommended for pregnant women. Omega 3 has anti-inflammatory properties and is essential for maintaining good health.
Read More

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 29 Researches
7.1
  • All Researches
We analyzed the impact of different fatty acid-derived acylcarnitines on heart health. The study found that saturated and monounsaturated acylcarnitines, especially trans-elaidoylcarnitine, significantly impaired heart function and mitochondrial activity, leading to cardiotoxicity.

In contrast, omega-3-derived acylcarnitines, like eicosapentaenoylcarnitine and docosahexaenoylcarnitine, were found to be safe, having little to no negative effect on heart function and cell viability. Overall, this research suggests that omega-3 fatty acids may be a safer option for those facing cardiac challenges.
Read More
9
High-dose omega-3 improves heart function
We explored how omega-3 polyunsaturated fatty acids (PUFAs) can help manage heart failure by analyzing 14 randomized controlled trials involving over 9,000 participants.

Our findings revealed that high doses—between 2000 and 4000 mg daily—taken for at least a year, remarkably improved heart function.

However, lower doses or shorter treatment periods didn’t show the same benefits. Notably, there were no increased risks of adverse events or dropout rates in those taking omega-3 compared to control groups.
Read More
We examined the relationship between plasma omega-3 levels and heart failure (HF), focusing on how this affects mortality in patients with existing HF. Our analysis of the UK Biobank, which included nearly 272,000 participants without HF, showed that higher omega-3 levels were linked to a 21% lower risk of developing HF over nearly 14 years.

For those already diagnosed with HF, higher omega-3 levels significantly reduced the risk of all-cause and cardiovascular mortality by around 50%. These findings suggest that boosting omega-3 intake could be beneficial for heart health.
Read More
9
Omega-3 benefits African Americans’ heart health
We observed that the role of omega-3 fatty acids in heart health showed promising results specifically for African Americans. By comparing matched groups from the VITAL trial, we found that omega-3 supplementation significantly reduced the risk of myocardial infarction in African Americans, while no such benefit was seen in non-Hispanic whites.

This suggests that genetic or lifestyle factors may influence the effectiveness of these supplements. Our findings highlight the importance of further research to better understand how race affects responses to omega-3 supplementation.
Read More
We explored the impact of eicosapentaenoic acid (EPA), a type of omega-3 fatty acid, on heart disease through a significant study known as the VITAL trial. This study involved nearly 26,000 older adults in the U.S. and aimed to determine the effects of daily EPA supplementation on cardiovascular events over an average follow-up of 5.3 years.

Initially, the results from VITAL seemed to show that omega-3 supplementation had no significant effect on major cardiovascular disease (CVD) events. However, by applying Bayesian methods and considering prior research in the field, we observed a more nuanced outcome. Our analysis suggested that taking EPA regularly could significantly reduce the risk of coronary heart disease events, while not showing similar benefits for stroke.

This finding supports the use of omega-3 fatty acids as a preventive measure for heart health, especially regarding coronary events. Although we didn't find evidence of a benefit for all types of cardiovascular events, the enhanced understanding gained from this reanalysis contributes valuable insights for both clinicians and patients considering omega-3 supplementation for heart disease prevention.
Read More

User Reviews

USERS' SCORE
Good
Based on 6 Reviews
8.1
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Mood and heart benefits
1 people found this helpful
Fish Oil is remarkable! I believe it's assisting with my mood swings. Initially bought for my daughter, we now share it. I've noticed I'm less irritable, and it appears beneficial for heart disease and my autoimmune issues. The softgels are easy to swallow. I recommend purchasing, and I’ll continue using it!
Read More
7.5
Supports heart health
427 people found this helpful
Wonderful! This fish oil is excellent as Omega 3 can reduce the risk of heart disease and improve blood circulation. It enhances cognitive functions and helps lower blood pressure. My family consistently takes omega, and the price-quality ratio is ideal. The capsules are quite large but easy to swallow.
Read More
8
Nervous system benefits
1 people found this helpful
The quality is superb with a halal composition. It's beneficial for heart disease, immunity, and brain development. It’s recommended for pregnant women. Omega 3 has anti-inflammatory properties and is essential for maintaining good health.
Read More
9
Family heart support
Omega 3 can reduce heart disease risk, enhance blood circulation, and improve cognitive functions. My family takes omega regularly, and the capsules are easy to swallow. There were no unpleasant gastrointestinal issues.
Read More
7.5
Improved heart function
1 people found this helpful
Excellent vitamins! After taking them, my skin has improved and my hair is less split. Fish oil is also beneficial for heart disease and blood circulation.
Read More

Frequently Asked Questions

9
Mood and heart benefits
1 people found this helpful
Fish Oil is remarkable! I believe it's assisting with my mood swings. Initially bought for my daughter, we now share it. I've noticed I'm less irritable, and it appears beneficial for heart disease and my autoimmune issues. The softgels are easy to swallow. I recommend purchasing, and I’ll continue using it!
9
Family heart support
Omega 3 can reduce heart disease risk, enhance blood circulation, and improve cognitive functions. My family takes omega regularly, and the capsules are easy to swallow. There were no unpleasant gastrointestinal issues.
7.5
Supports heart health
427 people found this helpful
Wonderful! This fish oil is excellent as Omega 3 can reduce the risk of heart disease and improve blood circulation. It enhances cognitive functions and helps lower blood pressure. My family consistently takes omega, and the price-quality ratio is ideal. The capsules are quite large but easy to swallow.
7.5
Improved heart function
1 people found this helpful
Excellent vitamins! After taking them, my skin has improved and my hair is less split. Fish oil is also beneficial for heart disease and blood circulation.
7.5
Allergy reduction
Great value! Fish oil can reduce allergy symptoms and protects blood vessels. The taste is not too fishy, and the dose of omega is sufficient.
We examined the relationship between plasma omega-3 levels and heart failure (HF), focusing on how this affects mortality in patients with existing HF. Our analysis of the UK Biobank, which included nearly 272,000 participants without HF, showed that higher omega-3 levels were linked to a 21% lower risk of developing HF over nearly 14 years.

For those already diagnosed with HF, higher omega-3 levels significantly reduced the risk of all-cause and cardiovascular mortality by around 50%. These findings suggest that boosting omega-3 intake could be beneficial for heart health.
8
Eicosapentaenoic Acid reduces heart risks
We evaluated the impact of eicosapentaenoic acid (EPA) on heart disease, specifically focusing on its potential to reduce the risk of sudden cardiac death (SCD) and cardiovascular mortality (CVD mortality). Through a systematic review and meta-analysis, we gathered insights from 10 prospective cohort studies involving a total of 310,955 participants over an average follow-up period of 8.7 years.

Our analysis revealed that higher levels of omega-3 fatty acids, including EPA, in the blood were associated with a lower risk of both SCD and CVD mortality. Specifically, we found that individuals with high circulating levels of EPA and other omega-3s had a significantly reduced hazard ratio of 0.55 for SCD compared to those with lower levels. This suggests a protective effect linked to increased EPA intake.

Furthermore, our sub-analysis indicated that higher percentages of EPA and another omega-3 called DHA in the blood also correlated with a reduced risk of adverse cardiac events. These findings highlight the promising role of EPA as a beneficial component in cardiovascular health strategies.

Overall, the evidence suggests that increasing our intake of EPA could serve as an effective measure to lessen the incidence of serious heart-related issues, making it a topic worth considering in future dietary recommendations.
8
Omega-3 reduces heart disease risk
We explored the effectiveness of icosapent ethyl, a form of omega-3 fish oil, in lowering heart disease rates among high-risk patients with varying cholesterol levels.

In a clinical trial with statin-treated individuals who had elevated triglycerides, it was found that those taking icosapent ethyl experienced significantly fewer cardiovascular events compared to those on a placebo.

Notably, this benefit was seen regardless of their baseline low-density lipoprotein cholesterol (LDL-C) levels, indicating positive outcomes even for patients with well-controlled cholesterol.
8
Omega-3s beneficial for heart health
We explored the effects of dietary omega-3 polyunsaturated fatty acids (PUFAs) on heart disease and their potential in food fortification. Recent clinical trials indicate that incorporating omega-3 PUFAs into our diets can significantly lower the risk of heart disease, improve blood pressure, and enhance lipid profiles.

Food fortification with omega-3s has seen advancements in technology, including methods that ensure stability and bioaccessibility. While there’s promising data supporting omega-3s for better heart health, we recognize that more research is needed to fully harness their benefits for cardiovascular disease prevention.
7
EPA shows promise for heart health
We examined the effect of eicosapentaenoic acid (EPA) on diabetic cardiomyopathy (DC), a condition that can lead to heart failure. In our study, EPA was found to protect against DC in diabetic mice by targeting harmful macrophages.

Interestingly, EPA shifted the macrophages from a damaging state to a protective one. This change helps reduce injury to heart cells, showcasing EPA's potential as a new treatment approach for managing heart issues in diabetes.

Overall, we discovered that EPA could play a significant role in heart health for those suffering from diabetes.
9
High-dose omega-3 improves heart function
We explored how omega-3 polyunsaturated fatty acids (PUFAs) can help manage heart failure by analyzing 14 randomized controlled trials involving over 9,000 participants.

Our findings revealed that high doses—between 2000 and 4000 mg daily—taken for at least a year, remarkably improved heart function.

However, lower doses or shorter treatment periods didn’t show the same benefits. Notably, there were no increased risks of adverse events or dropout rates in those taking omega-3 compared to control groups.

References

  1. Liepinsh E, Gukalova B, Krims-Davis K, Kuka J, Leduskrasta A, et al. EPA and DHA acylcarnitines are less cardiotoxic than are saturated and monounsaturated long-chain acylcarnitines. Biofactors. 2025;51:e70014. doi:10.1002/biof.70014
  2. Xu J, Peng T, Kong L, Wei N. A global analysis of the burden of ischemic heart disease attributable to diet low in ω-3 fatty acids between 1990 and 2021. BMC Cardiovasc Disord. 2025;25:188. doi:10.1186/s12872-025-04620-z
  3. Horii K, Ono K, Sumi T, Higashihara M, Zaima N, et al. Eicosapentaenoic acid prevents atrial electrocardiographic impairments and atrial fibrillation in high fat diet mice. J Physiol Sci. 2025;75:100014. doi:10.1016/j.jphyss.2025.100014
  4. Dawczynski C, Drobner T, Weidauer T, Schlattmann P, Kiehntopf M, et al. Reduction of cardiovascular risk factors by the diet - Evaluation of the MoKaRi concept by a parallel-designed randomized study. Lipids Health Dis. 2025;24:88. doi:10.1186/s12944-025-02500-1
  5. Aggarwal R, Bhatt DL, Steg PG, Miller M, Brinton EA, et al. Cardiovascular Outcomes With Icosapent Ethyl by Baseline Low-Density Lipoprotein Cholesterol: A Secondary Analysis of the REDUCE-IT Randomized Trial. J Am Heart Assoc. 2025;14:e038656. doi:10.1161/JAHA.124.038656
  6. Tseng PT, Zeng BY, Hsu CW, Liang CS, Stubbs B, et al. The Optimal Dosage and Duration of ω-3 PUFA Supplementation in Heart Failure Management: Evidence from a Network Meta-Analysis. Adv Nutr. 2025;16:100366. doi:10.1016/j.advnut.2025.100366
  7. Hemmati R, Bahrami Zanjanbar D, Shishesaz MI, Soleimani A, Yari T. The impact of Omega-3 supplementation on arrhythmia reduction in acute coronary syndrome patients: a randomized clinical trial. J Complement Integr Med. 2025;22:173. doi:10.1515/jcim-2024-0427
  8. Wang Y, Wu G, Wang Y, Rehman A, Yu L, et al. Recent developments, challenges, and prospects of dietary omega-3 PUFA-fortified foods: Focusing on their effects on cardiovascular diseases. Food Chem. 2025;470:142498. doi:10.1016/j.foodchem.2024.142498
  9. Jawad MA, O'Keefe JH, Tintle N, O'Keefe EL, Franco WG, et al. Association of Plasma Omega-3 Levels With Incident Heart Failure and Related Mortalities. Mayo Clin Proc. 2024;99:1895. doi:10.1016/j.mayocp.2024.08.007
  10. Lee YQ, Tan KH, Chong MF. Biomarkers of PUFA and cardiovascular risk factors and events in healthy Asian populations: a systematic review. Br J Nutr. 2024;132:1474. doi:10.1017/S0007114524002708
  11. Li J, Nan W, Huang X, Meng H, Wang S, et al. Eicosapentaenoic acid induces macrophage Mox polarization to prevent diabetic cardiomyopathy. EMBO Rep. 2024;25:5507. doi:10.1038/s44319-024-00271-x
  12. Ryuno Y, Kobayashi JI, Fujimoto Y, Dotare T, Matsue Y, et al. Effect of an Enteral Formula Enriched With ω-3 Fatty Acids, Carnitine, and Vitamin D on Body Weight, Heart Weight, and Blood Biochemical Parameters in a Dahl Rat Heart Failure Model. J Cardiovasc Pharmacol. 2024;84:590. doi:10.1097/FJC.0000000000001637
  13. Sun S, Hara A, Johnstone L, Hallmark B, Watkins JC, et al. Optimal Pair Matching Combined with Machine Learning Predicts a Significant Reduction in Myocardial Infarction Risk in African Americans Following Omega-3 Fatty Acid Supplementation. Nutrients. 2024;16. doi:10.3390/nu16172933
  14. Ahmadi M, Askari VR, Shahri B, Mousavi Noghab SM, Jarahi L, et al. Omega-3 fatty acids effectively mitigate high-sensitivity C-reactive protein (hs-CRP) biomarker of inflammation in acute myocardial infarction patients: a randomized, double-blind, placebo-controlled clinical trial. Naunyn Schmiedebergs Arch Pharmacol. 2025;398:881. doi:10.1007/s00210-024-03330-1
  15. Chen HC, Tai CJ, Huang JY, Kuo TA, Huang YD, et al. Associations of fish oil with cardiovascular disease events: results from the Taiwan longitudinal study in aging. BMC Public Health. 2024;24:1979. doi:10.1186/s12889-024-19512-8
  16. Yu Y, Gao M, Xu H. Ginger Extract and Omega-3 Fatty Acids Supplementation: A Promising Strategy to Improve Diabetic Cardiomyopathy. Physiol Res. 2024;73:351.
  17. Hamaya R, Cook NR, Sesso HD, Buring JE, Manson JE. A Bayesian Analysis of the VITAL Trial: Effects of Omega-3 Fatty Acid Supplementation on Cardiovascular Events. Am J Clin Nutr. 2025. doi:10.1016/j.ajcnut.2025.02.028
  18. Patil T, Gregory M, Savona N, Jarmukli N, Leonard CE. Evaluating the Real-World Safety of Icosapent Ethyl Versus Omega-3 Polyunsaturated Fatty Acid in Nationwide US Veterans Cohort: Examining Atrial Fibrillation and Bleeding Endpoints. Clin Drug Investig. 2025;45:69. doi:10.1007/s40261-024-01417-4
  19. Kim JY, Kong SYJ, Jung E, Cho YS. Omega-3 Fatty Acids as Potential Predictors of Sudden Cardiac Death and Cardiovascular Mortality: A Systematic Review and Meta-Analysis. J Clin Med. 2024;14. doi:10.3390/jcm14010026
  20. Capece U, Gugliandolo S, Morciano C, Avolio A, Splendore A, et al. Erythrocyte Membrane Fluidity and Omega-3 Fatty Acid Intake: Current Outlook and Perspectives for a Novel, Nutritionally Modifiable Cardiovascular Risk Factor. Nutrients. 2024;16. doi:10.3390/nu16244318
  21. Fukuda T, Nakajima T, Hasegawa T, Amano H, Arikawa T, et al. Relationship Between Serum ω-3 Polyunsaturated Fatty Acid Concentration and Fatty Acid Fraction of Epicardial Adipose Tissue in Patients With Cardiovascular Disease. Cureus. 2024;16:e73417. doi:10.7759/cureus.73417
  22. O'Keefe EL, O'Keefe JH, Abuissa H, Metzinger M, Murray E, et al. Omega-3 and Risk of atrial fibrillation: Vagally-mediated double-edged sword. Prog Cardiovasc Dis. 2024. doi:10.1016/j.pcad.2024.11.003
  23. Choi GY, Calder PC. The differential effects of eicosapentaenoic acid and docosahexaenoic acid on cardiovascular risk factors: an updated systematic review of randomized controlled trials. Front Nutr. 2024;11:1423228. doi:10.3389/fnut.2024.1423228
  24. Amangurbanova M, Daher R, Asbeutah AA, Vemuri B, Mirza H, et al. Higher epicardial adipose tissue volume is associated with higher coronary fatty plaque volume and is regulated by waist circumference but not EPA+DHA supplementation. J Clin Lipidol. 2024;18:e773. doi:10.1016/j.jacl.2024.06.006
  25. Kumakura H, Funada R, Matsuo Y, Iwasaki T, Nakashima K, et al. Eicosapentaenoic Acid Level Predicts Long-Term Survival and Cardiovascular or Limb Event in Peripheral Arterial Disease. Ann Vasc Dis. 2024;17:135. doi:10.3400/avd.oa.23-00079
  26. Xiao Y, Chen Y, Pietzner A, Elbelt U, Fan Z, et al. Circulating Omega-3 Polyunsaturated Fatty Acids Levels in Coronary Heart Disease: Pooled Analysis of 36 Observational Studies. Nutrients. 2024;16. doi:10.3390/nu16111610
  27. Asbeutah AA, Daher R, Malik A, Hariri E, Alfaddagh A, et al. The Effect of Eicosapentaenoic and Docosahexaenoic Acid Supplementation on Coronary Artery Calcium Progression in Subjects With Diabetes and Coronary Artery Disease: A Secondary Analysis of a Randomized Trial. Am J Cardiol. 2024;225:98. doi:10.1016/j.amjcard.2024.06.001
  28. Sudo Y, Morimoto T, Tsushima R, Oka A, Sogo M, et al. Eicosapentaenoic Acid and the Outcomes in Older Patients Undergoing Atrial Fibrillation Ablation. J Am Heart Assoc. 2024;13:e033969. doi:10.1161/JAHA.123.033969
  29. Miyauchi K, Iwata H, Nishizaki Y, Inoue T, Hirayama A, et al. Randomized Trial for Evaluation in Secondary Prevention Efficacy of Combination Therapy-Statin and Eicosapentaenoic Acid (RESPECT-EPA). Circulation. 2024;150:425. doi:10.1161/CIRCULATIONAHA.123.065520
image